Joe Kelly's classic storyline concludes! As the world-ending threat that LL&L has been preparing Deadpool to fight looms, Wade struggles with a crisis of conscience. Can he really be the Mithras, prophesied to save the world? Not to worry, because LL&L has a possible replacement all lined up: Captain America! The aftermath of this cosmic conflict leaves Deadpool more unstable than usual - but when a familiar woman from his past returns, everything Wade Wilson knows about himself will be called into question!